Sussel Lab

Welcome

The laboratory of Dr. Sussel is focused on understanding the complex transcriptional networks that regulate development, differentiation and function of the pancreas. To date, only a handful of regulatory factors involved in pancreas development have been thoroughly characterized and many of the molecular pathways that specify islet cell differentiation and function are poorly understood. For this reason, we are using cutting edge molecular biology techniques paired with advanced mouse genetics to more clearly define the roles of coding and non-coding genes involved in the development of the pancreas, the regulation of islet cell differentiation, and endocrine function.
 
Read more about our work on our research page. 

• Congratulations Dr. Moss! Nicole successfully defended her thesis on 3/31/23 - and graduated 5/21/23, amazing work!!!

• Bryce Hopwood has been promoted to lab manager, congratulations Bryce!

• Tori Hoelscher is our new PRA, welcome!

• David will be starting his independent research career in April 2023 as Assistant Professor at the University of Michigan Medical School in the Department of Pharmacology with membership in the Caswell Diabetes Institute!

• Congratulations Dr. Theis! Alex successfully defended her thesis on 4/15/22 - amazing work!!!

• Congratulations Dylan for his officially funded F31 award, “CHD4 mediated transcriptional regulation of pancreatic beta cell development and function”

• David has been awarded an NIH K99/R00 transition to independence award

• Bryce Hopwood is our new PRA, welcome!

• Chris Schaaf and Maria Hansen have joined the lab

• Nicole has been named a 2021 RNA Bioscience Initiative Scholar!

• Congratulations to Lori for being named Associate Vice Chancellor for Basic Research at the CU Anschutz campus

• Nicole published two new papers: mRNA Processing: An Emerging Frontier in the Regulation of Pancreatic β Cell Function and Selection and characterization of mutants defective in DNA methylation — great work!

• Nicole has received an F31 to study RNA Regulation in the Pancreatic Beta Cell, congratulations!

• Dylan has officially joined the Sussel lab as a graduate student and has passed his prelims, great work!

• David’s collaborative paper with Dylan, Elliott, and Eloise is now out at Development

• Laura’s paper has been published in Stem Cell Reports

• We are excited to have Cailin join the lab as our Professional Research Assistant

• Ruth’s beautiful paper is officially out in Cell Metabolism

• Welcome to postdoc world Dr. Elena Abarinov, PhD

• Welcome Elliott, our newest graduate student, to the lab

• Laura has been awarded an F32 Postdoctoral NIH Fellowship

• Congratulations to Dylan who will be starting his PhD in the Molecular Biology Program at UC Denver

• Laura’s and David’s Preview article “Fishing for Beta Cells” was published in Developmental Cell

• Alex has been awarded an F31 Predoctoral NIH Fellowship

• Congratulations to Ruth for her very successful thesis defense

• Congratulations to Elena for a great PhD defense

• Congratulations to Alex for passing her comps

• Congratulations to David on receiving the American Diabetes Association Postdoctoral Fellowship award

• Congratulations to Ruth on having her review published in Diabetes  

• Congratulations to Laura on receiving the inaugural  Guild ACORN Postdoctoral Fellowship

• Congratulations to Lori on being the inaugural recipient of the Sissel and Findlow Family Stem Cell Endowed Chair